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Vitamin supplement may delay diabetes in select groups, researchers say

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High-dose vitamin D supplements could help reduce diabetes risk among certain groups, according to new research from Tufts University.

In a large clinical trial, researchers performed genetic testing of more than 2,000 U.S. adults with prediabetes after they received 4,000 units per day of vitamin D supplements, then compared them to a placebo group.

An earlier study showed no significant reduction in diabetes risk in the group receiving vitamin D supplementation, but when the researchers looked closer, they found a benefit for certain genetic groups.

For the new study, the Tufts researchers compared participants who appeared to benefit from vitamin D supplementation to those who did not, then examined how outcomes differed across three common variants of the vitamin D receptor gene.

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People who had certain versions of a vitamin D-related gene (called AC or CC) were 19% less likely to get diabetes when they took vitamin D compared to people who took a placebo, according to a university press release.

Participants with another genetic variant (AA) showed no benefit from supplementation.

Vitamin D seems to work by attaching to a specific “receiver” in the body called the vitamin D receptor, the researchers discovered. These receptors are found in many places, including the pancreas, the organ that makes insulin.

The findings were published last week in JAMA Network Open.

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“Our finding is an example of the emerging science of precision nutrition or precision medicine, in which an intervention can be tailored to the needs of individuals according to their genetic makeup and disease risk,” Bess Dawson-Hughes, the study’s lead author and a senior scientist at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, told Fox News Digital.

“Taking a vitamin D supplement daily is an easy, inexpensive and generally safe approach to reducing diabetes risk,” she added. “In principle, this could involve a single, relatively inexpensive genetic test.”

There were some limitations to the study, the researchers noted, including that this was a secondary analysis rather than a primary randomized comparison.

“Like any other first observation, this finding needs to be replicated in a future study,” the researcher said.

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The study only included individuals with prediabetes, which could limit relevance to broader populations. The results seen in specific genetic groups need to be confirmed in more studies before doctors can use them in patient care.

The authors emphasized that people should not start taking high doses of vitamin D as a diabetes prevention strategy based on this study.

“It is too early to make specific recommendations for the general population,” Dawson-Hughes said. 

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Current recommendations suggest that most adults get about 600 IU of vitamin D daily (ages 1–70) and 800 IU for those over 70. However, previous studies have shown that taking very high doses can be harmful for older adults.

“There is some evidence, from my laboratory and others, that the relatively high blood levels of 25-hydroxyvitamin D needed to achieve the diabetes risk reduction have been associated with an increased risk of falling in older adults,” Dawson-Hughes noted.  

“I would not advise older adults to take a daily dose of 4,000 IU of vitamin D without first consulting with their doctors.”

This new study raises another question, according to Dawson-Hughes: Would vitamin D supplementation in adults with the responsive genotypes lower the risk of developing prediabetes, the forerunner to Type 2 diabetes? 

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“This is important because prediabetes is not a benign condition,” she said. “Adults with prediabetes also have an increased risk of cardiovascular disease.”

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Kentucky man accused of kidnapping, killing woman and keeping her body under trailer before disposal

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A Kentucky man is set to go to trial next year after he allegedly abducted and killed a woman, wrapped her body, stored it under his trailer and dumped it on the side of a road seven years ago, according to authorities.

Ryan “Todd” Crawley had his trial date set for May 17–28 of next year in connection with the 2019 death of April Arnett, the Scott County Circuit Court said, according to WKYT.

He was indicted earlier this year on charges of murder, kidnapping and evidence tampering. Crawley pleaded not guilty to the murder and kidnapping charges after he previously pleaded guilty to evidence tampering and abuse of a corpse.

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Crawley has pleaded not guilty to the murder and kidnapping charges, and those charges remain pending. His attorneys have argued that the timing of the new charges — nearly seven years after Arnett’s death — raises questions about the case. Court documents allege Crawley was involved in Arnett’s kidnapping and killing.

His lawyers, who have sought to maintain their client’s innocence on the more serious charges, have highlighted that the murder and kidnapping charges were filed nearly seven years after the 2019 incident.

On Aug. 17, 2019, at about 9 p.m., Kentucky State Police were notified about a body later identified as Arnett that was found off KY Highway 2328, also known as Old Lexington Road, in Madison County.

Police say the discovery was made four days after Arnett’s alleged death in Scott County.

Crawley allegedly wrapped up Arnett’s body before storing it under his trailer, court documents say, according to WLEX.

Four other people, including the defendant’s cousin Ronald Crawley, were charged with helping kidnap Arnett.

Authorities said the two Crawleys drove into Madison County over the Old Clays Ferry Bridge with Arnett’s body wrapped in a tarp with cinder blocks attached. The pair attempted to toss her body into the water, but it became stuck on a guy wire, at which point the men put Arnett’s body back into the vehicle and dumped it off the side of the road, where she was ultimately found.

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Ronald Crawley was arrested in Oregon in 2019 after allegedly fleeing to the state.

Arnett was a mother of three, according to her obituary, which said she “will forever be known for her big heart and infectious smile.”

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Two planes come within 500 feet of each other while approaching JFK Airport in latest close call

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Two planes had a close call while approaching John F. Kennedy International Airport in New York City on Monday, with flight-tracking data reportedly showing they came within roughly 500 feet vertically of each other.

The incident came one day after a separate plane struck a light pole and damaged a bakery truck while landing in New Jersey, marking the latest in a string of aviation close calls.

Air traffic control audio shows a controller at JFK alerted the pilot of a Delta flight, operated by its subsidiary Endeavor Air, to a smaller aircraft flying less than 500 feet above them, according to ABC7.

Data from Flightradar24 cited by ABC7 shows the planes were separated by about 475 feet vertically as their paths crossed. The Endeavor aircraft was at about 2,100 feet, while the Cirrus plane was at roughly 2,575 feet.

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The Federal Aviation Administration said Endeavor Air Flight 5289 was on final approach to Runway 22L around 5:15 p.m. Monday when a Cirrus SR22 crossed overhead while preparing to land on Runway 22R.

“Air traffic control provided traffic advisories to both pilots, and each reported the other in sight,” the FAA said. “The required separation was maintained.” 

The Endeavor pilot told controllers the flight crew received a traffic advisory, followed by a resolution advisory from the aircraft’s collision avoidance system, ABC7 reported.

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Audio captured the exchange between controllers and the flight crew.

“Endeavor 5289 yeah I’m not talking to him. He’s 500 feet above you now left to right half a mile in front of you,” a controller said, according to the report.

“And tower Endeavor 5289 he just flew about 500 feet right over so looks like he’s taking a left turn now,” the pilot responded.

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Monday’s incident is the latest in a series of close calls that have drawn increased scrutiny from federal regulators and lawmakers.

On Sunday, a United Airlines flight traveling from Venice, Italy, to Newark Liberty International Airport struck a light pole and damaged a bakery truck during its descent around 2 p.m. The 221 passengers and 10 crew members aboard were not injured, and the plane landed safely.

JFK also experienced a close call last month when two passenger jets came too close on approach, triggering onboard collision warnings and a federal investigation.

In that incident, the FAA said Republic Airways Flight 4464 performed a go-around after missing its approach path and flying too close to Air Canada Express Flight 8554, which had been cleared to land on a parallel runway.

Fox News Digital has reached out to the FAA, Delta and Cirrus for comment.

Fox News Digital’s Greg Wehner and Julia Bonavita contributed to this report.

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Bryson DeChambeau Pivoting To YouTube, ‘Tournaments That Want Me’ If LIV Golf Comes To End

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DeChambeau suggested that he could be knocked with major penalties from the PGA Tour if he decides to return
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