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Thinking about peptides? Doctors reveal key dos and don’ts as ‘Wild West’ market grows
The peptide boom is under scrutiny as the FDA weighs easing restrictions on several drugs in the category.
Peptides, which are short chains of amino acids that serve as the building blocks of proteins, have gained popularity among wellness influencers and fitness gurus as a means of building muscle, healing injuries or appearing younger.
Similar to how GLP-1s (glucagon-like peptide-1 agonists) suppress appetite and trigger weight loss, peptides can signal other functions, like the release of growth hormones.
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But unlike GLP-1 drugs — which were extensively studied and regulated — many peptides lack comparable evidence and oversight, said New York endocrinologist Dr. Philip Rabito, adding that some are “not reviewed by the FDA for safety, effectiveness or quality before marketing.”
Peptides under FDA review, including BPC-157, are often marketed for tendon and gut healing, injury recovery and inflammation reduction, despite warnings about the risks of unapproved treatments.
Even as regulators consider loosening restrictions, the market has been widely described as a “Wild West,” with various versions sold online without a prescription.
In an interview with Fox News Digital, board-certified internist and longevity expert Dr. Amanda Kahn, who prescribes peptides in her own New York practice, confirmed that interest has grown “significantly” across the U.S.
Peptides are popular because they “sit at the intersection of wellness optimization and medicine,” according to the doctor.
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“As a class, they are targeted biosimilar molecules that can influence specific pathways like inflammation, recovery and metabolism in a way that feels more biologically synergistic than traditional pharmaceuticals,” she said.
Most patients spend a few hundred to thousands of dollars on these drugs per month, according to Kahn. Costs can be high because peptides are often custom-made and must meet strict quality and sterility standards.
“At the same time, patients today are far more proactive and invested in their health,” Kahn added. “They’re not waiting to get sick; they want to feel better, recover faster and age more intentionally.”
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Peptides have evolved rapidly from just a few years ago, when they were largely focused on weight loss, the expert said, with growing interest in energy, post-illness or injury recovery, muscle preservation and sleep quality.
But these drugs are not one-size-fits-all, experts warn, especially when not prescribed by a professional or cleared by a reputable pharmacy.
Experts shared the following guidance on using peptides.
Kahn recommends using peptides with “a clear, clinical rationale, not just because they’re trending.”
“Think of peptides as part of a broader health plan, not a standalone solution,” she advised.
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Kahn said patients often come into her practice focused on weight or appearance, but in-depth testing may uncover underlying issues such as inflammation, metabolic dysfunction, hormonal imbalance or recovery deficits.
“It’s both aesthetic and medical, but the trend in my internal medicine practice has always been toward specific health concerns,” she added.
Dr. Kent Bradley, chief medical officer at 10X Health in California, recommends approaching peptides with “curiosity and rigor” and discussing the science with a physician.
“Work with a clinician who provides a baseline of biomarkers before you introduce peptides,” he recommended during an interview with Fox News Digital. “You will need to know where you’re starting in order to measure the impact.”
Peptides should always be purchased from “reputable compounding pharmacies by prescription,” Kahn emphasized.
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“While they are powerful signaling molecules, when used appropriately, they can be very safe and effective,” she said. “When used incorrectly, [with] the wrong dose, wrong indication or poor sourcing, they can be dangerous or ineffective.”
She added, “The key is clinical oversight, proper selection and individualized use.”
The current peptide ecosystem — including unlicensed providers and “gray market” access — is “more dangerous than the molecules themselves,” Kahn warned.
It’s important to use pharmacies that meet FDA 503A or 503B regulations to ensure consumer safety, the expert added.
Multiple peptides should not be combined without understanding how they interact with each other, nor should they be injected as mixtures, Kahn warned.
“Don’t treat them as risk-free supplements,” she said. “They are biologically active and should be used thoughtfully.”
“Peptides should be cycled, paused and re-assessed — don’t ‘set it and let it go.’”
Dose-response and drug interactions require medical oversight, and peptides should be prescribed by a doctor, according to Bradley. Some products that are marketed as “natural” may still have the capacity to do harm to the body, he warned.
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Fundamental pillars of health, like sleep, nutrition and exercise, should be addressed before using a peptide as a “shortcut” to fix health complications, Kahn said.
Bradley agreed, adding that “the same instinct that drives patients toward unnecessary surgery drives them toward complex peptide stacks when the real leverage is upstream and boring.”
Kenny Santucci, a fitness expert and founder of Strong New York, shared with Fox News Digital that he takes peptides for muscle building himself – but noted that it’s not right for everyone.
Especially for younger individuals, whose bodies are “already working at optimal levels,” peptides may be unnecessary, he said.
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“If you take care of yourself — if you’re eating right, sleeping right, working out — you probably don’t need much,” he said.
“I think as you get older, these things start to help out a little bit, or if you suffer from an injury and you want to take something that will help repair the tissue quicker, that’s great.”
Seattle Storm player Lexie Brown has been in the WNBA since 2018, and won a championship with the Chicago Sky in 2021. In recent years, she’s taken notice of how the culture and image of the WNBA has changed since Caitlin Clark’s arrival in 2024.
“Has it changed how people view the WNBA? Absolutely. I think unfortunately, our value, the respect that we got has been directly attached to how much money we make and it’s not rocket science to see that since her arrival, and the rest of that 2024 class, the WNBA has skyrocketed. I’m not gonna act like that’s not a coincidence,” Brown told Fox News Digital.
“I think that people are taking the league more seriously, I think people are taking us more seriously as professional athletes. And I think if you consider that a culture shift, I would say, absolutely.”
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Brown admitted that injuries and her battle with Crohn’s Disease has kept her further from the court over the last two seasons during Clark’s rise, only playing in 40 total games since 2024.
Still, Brown witnessed the phenomena and controversy as a competitor.
“Do I think there were instances of excessive physicality? For sure,” Brown said when asked about the on-court play involving the 2024 draft class. “But I think that happens at all leagues, to rookies, the young players, I think that’s just the competitive nature of things… I feel like if you watch the season, you can come to your own conclusions about that. I’ve seen a lot of other excessive plays throughout my years.”
Brown pointed to when she suffered a concussion during an instance of ‘excessive physicality’ in her third season, as a member of the Minnesota Lynx.
“It happens, unfortunately,” she said.
Clark’s 2024 entry into the WNBA catalyzed record-breaking viewership, sold-out arenas and financial growth for the league.
But along with the growth came viral debate about on-court physicality and media coverage, especially among many of the new fans Clark brought to the sport. A few times during her rookie year, Clark suffered hard contact from certain opponents. Each of those moments ignited heated social media debates.
“She was a rookie that came in, that is super talented, and was number one on everyone’s scouting report. So you’re gonna get the best defender, you’re gonna get the most physical one, and I think it was just something that she had never seen before. And as a year went on, she adjusted and got used to it,” Brown said.
“It was hard at first for her to deal with that learning curve, growing pains, and you know, I think her fans kind of were like a little taken aback by the physicality of the WNBA, but I think like I said before, they allowed her to grow and learn through that, and she came out on top of the end.”
Brown herself has developed a complex dynamic with the hordes of new fans who have come to the WNBA since Clark’s arrival.
“There’s now a greater separation between fans and players… we were such like a niche, small community, tight-knit community for so long, and the WNBA has finally broken into this, like the mainstream sports media space, which is everything that we’ve asked for maybe we wouldn’t have this new CBA, we wouldn’t have these new contracts without it,” she said.
“So I’m not gonna say, I’m not appreciative… these eyes, these new viewers have changed so many of our lives.”
But Brown claims that one of the things she has had to deal with amid the WNBA’s growth in fandom is questioning of her validity as a WNBA player, amid her battle with Crohn’s disease and past injuries.
“I think because this explosion in the WNBA of interest in new eyes has happened in the last two years and I have virtually been not existent on the court because I’ve been dealing with Crohn’s and then last year I just simply didn’t get an opportunity to play. There’s been a lot of eyebrows raised as to how I got here if I deserve to be in the WNBA still, why I’m still on a roster with limited minutes, limited playing time, limited points per game, and the overall lack of empathy and sympathy,” she said.
“For me, it’s just having a little bit more empathy, understanding that myself and so many other players in this league are more than the stats.”
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Miranda Lambert delivers straight-shooting advice to rising country star in surprise bathroom encounter
Country star Lauren Alaina is sharing how Miranda Lambert gave her a reality check about the music industry during an unexpected first meeting.
Alaina, 31, recently recalled the moment during an appearance on “Taste of Country Nights.” She was asked who had given her some of the best advice in both her career and personal life, and she said that Lambert was responsible for giving her some solid tips.
“Miranda Lambert — I ran into at the BMI Awards, in the bathroom. It was my first time meeting her, and she was like, ‘Don’t you let this town or anybody change who you are. You’re a sweet Southern girl, and you stay that way,’” the “Road Less Traveled” singer shared.
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“I didn’t even know she knew who I was. It was the sweetest moment ever,” she added.
Alaina first appeared in the music industry at 15 years old on the stage of “American Idol.” She made it all the way through the competition singing show to the finals in 2011. She came in second place as Scotty McCreery took first.
Lambert’s advice comes after she previously opened up about leaning deeper into her country roots.
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The 42-year-old country star revealed she embraced her inner cowgirl by picking up an adrenaline-heavy hobby — mounted shooting.
“I just started last year. I’m not good at all, but I love it,” Lambert shared on “The Joe Rogan Experience” last October.
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She said she was introduced to the sport by her friend, Ken Shane, a 10-time world champion in the discipline.
“I just never had the guts to go do it, you know? And finally, my husband was like, ‘Stop talking about it, and go out there and do it. Go out there and shoot with her. You’re gonna love it.’”
“Wow. And I got addicted immediately. It’s just like something different.”
According to the Cowboy Mounted Shooting Association, it is a “fast-action timed event using two .45-caliber single-action revolvers, each loaded with five rounds of specially prepared blank ammunition.” Competitors are scored based on time and accuracy, with points being taken off for dropping the gun, missing a balloon and other factors.
A prominent left-wing academic has sparked controversy for declaring that mass migration from Africa will serve as a “great irrigation” of French society.
The post French Academic Praises Mass Migration From Africa as a ‘Great Irrigation’ of Society appeared first on Breitbart.
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