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Thinking about peptides? Doctors reveal key dos and don’ts as ‘Wild West’ market grows

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The peptide boom is under scrutiny as the FDA weighs easing restrictions on several drugs in the category.

Peptides, which are short chains of amino acids that serve as the building blocks of proteins, have gained popularity among wellness influencers and fitness gurus as a means of building muscle, healing injuries or appearing younger.

Similar to how GLP-1s (glucagon-like peptide-1 agonists) suppress appetite and trigger weight loss, peptides can signal other functions, like the release of growth hormones.

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But unlike GLP-1 drugs — which were extensively studied and regulated — many peptides lack comparable evidence and oversight, said New York endocrinologist Dr. Philip Rabito, adding that some are “not reviewed by the FDA for safety, effectiveness or quality before marketing.”

Peptides under FDA review, including BPC-157, are often marketed for tendon and gut healing, injury recovery and inflammation reduction, despite warnings about the risks of unapproved treatments.

Even as regulators consider loosening restrictions, the market has been widely described as a “Wild West,” with various versions sold online without a prescription.

In an interview with Fox News Digital, board-certified internist and longevity expert Dr. Amanda Kahn, who prescribes peptides in her own New York practice, confirmed that interest has grown “significantly” across the U.S.

Peptides are popular because they “sit at the intersection of wellness optimization and medicine,” according to the doctor.

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“As a class, they are targeted biosimilar molecules that can influence specific pathways like inflammation, recovery and metabolism in a way that feels more biologically synergistic than traditional pharmaceuticals,” she said.

Most patients spend a few hundred to thousands of dollars on these drugs per month, according to Kahn. Costs can be high because peptides are often custom-made and must meet strict quality and sterility standards.

“At the same time, patients today are far more proactive and invested in their health,” Kahn added. “They’re not waiting to get sick; they want to feel better, recover faster and age more intentionally.”

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Peptides have evolved rapidly from just a few years ago, when they were largely focused on weight loss, the expert said, with growing interest in energy, post-illness or injury recovery, muscle preservation and sleep quality.

But these drugs are not one-size-fits-all, experts warn, especially when not prescribed by a professional or cleared by a reputable pharmacy.

Experts shared the following guidance on using peptides.

Kahn recommends using peptides with “a clear, clinical rationale, not just because they’re trending.”

“Think of peptides as part of a broader health plan, not a standalone solution,” she advised.

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Kahn said patients often come into her practice focused on weight or appearance, but in-depth testing may uncover underlying issues such as inflammation, metabolic dysfunction, hormonal imbalance or recovery deficits.

“It’s both aesthetic and medical, but the trend in my internal medicine practice has always been toward specific health concerns,” she added.

Dr. Kent Bradley, chief medical officer at 10X Health in California, recommends approaching peptides with “curiosity and rigor” and discussing the science with a physician.

“Work with a clinician who provides a baseline of biomarkers before you introduce peptides,” he recommended during an interview with Fox News Digital. “You will need to know where you’re starting in order to measure the impact.”

Peptides should always be purchased from “reputable compounding pharmacies by prescription,” Kahn emphasized.

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“While they are powerful signaling molecules, when used appropriately, they can be very safe and effective,” she said. “When used incorrectly, [with] the wrong dose, wrong indication or poor sourcing, they can be dangerous or ineffective.”

She added, “The key is clinical oversight, proper selection and individualized use.”

The current peptide ecosystem — including unlicensed providers and “gray market” access — is “more dangerous than the molecules themselves,” Kahn warned.

It’s important to use pharmacies that meet FDA 503A or 503B regulations to ensure consumer safety, the expert added.

Multiple peptides should not be combined without understanding how they interact with each other, nor should they be injected as mixtures, Kahn warned.

“Don’t treat them as risk-free supplements,” she said. “They are biologically active and should be used thoughtfully.”

“Peptides should be cycled, paused and re-assessed — don’t ‘set it and let it go.’”

Dose-response and drug interactions require medical oversight, and peptides should be prescribed by a doctor, according to Bradley. Some products that are marketed as “natural” may still have the capacity to do harm to the body, he warned.

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Fundamental pillars of health, like sleep, nutrition and exercise, should be addressed before using a peptide as a “shortcut” to fix health complications, Kahn said.

Bradley agreed, adding that “the same instinct that drives patients toward unnecessary surgery drives them toward complex peptide stacks when the real leverage is upstream and boring.”

Kenny Santucci, a fitness expert and founder of Strong New York, shared with Fox News Digital that he takes peptides for muscle building himself – but noted that it’s not right for everyone.

Especially for younger individuals, whose bodies are “already working at optimal levels,” peptides may be unnecessary, he said.

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“If you take care of yourself — if you’re eating right, sleeping right, working out — you probably don’t need much,” he said. 

“I think as you get older, these things start to help out a little bit, or if you suffer from an injury and you want to take something that will help repair the tissue quicker, that’s great.”

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Oregon burglary suspect nabbed after crashing SUV during police chase: video

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A burglary suspect was taken into custody and is now facing a slew of charges after crashing his SUV during a police pursuit in Oregon, according to authorities.

Clackamas County Sheriff’s Office deputies responded to a report of a burglary in the 17000 block of Southeast River Road on Tuesday at around 4 p.m.

A 911 caller had reported observing a man enter their garage and steal various items after reviewing home security footage, according to deputies.

When deputies arrived, the caller shared images of the suspect and told them that the man was driving a white Ford Explorer.

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Deputies later identified the suspect as Scotty Nicholas Oldfield. His vehicle was spotted by a deputy on Southeast Roethe Road before he sped off past the deputy.

Deputies began pursuing the vehicle and attempted to stop Oldfield. 

Oldfield eventually crashed into another occupied vehicle near Southeast Oatfield Road and Southeast Park Avenue and rolled the SUV he was driving before hitting an unoccupied parked vehicle.

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The driver of the other occupied vehicle declined medical treatment at the scene. 

Oldfield was taken into custody and transported to a local hospital to be treated for serious injuries.

When deputies searched Oldfield’s vehicle, they located suspected stolen items.

Oldfield was charged with several crimes, including second-degree burglary, first-degree theft, attempting to elude a police officer, reckless driving, reckless endangerment, DUII, identity theft, driving while suspended or revoked, third-degree assault (DUII) and criminal mischief.

Investigators later learned that Oldfield had multiple outstanding warrants out of Oregon and Washington state for charges such as failure to appear, DUII, driving while suspended, false information, identity theft, assault, reckless endangerment, robbery, malicious mischief and criminal trespass.

Investigators believe Oldfield may have targeted additional victims. Anyone with information about Oldfield’s criminal activity is urged to contact the sheriff’s office.

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How the media, in the digital age, help fuel a climate of anger and violence

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The media are part of the problem.

What problem? Well, there’s a long list. Take your pick.

In the pre-digital era, I used to say that cable news encouraged inflammatory rhetoric by lawmakers because so many of them wanted to break through the static and get their sound bite on the air.

Things are a thousand times more complicated now with the rise of podcasts, group chats, Snapchat, TikTok, X, Facebook, Instagram, Threads, YouTube and Substack. But the principle remains the same. How, amid this deafening noise, do you get heard?

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It’s a much angrier atmosphere now, and some attribute that to President Donald Trump. But he didn’t create this environment, he just exploited it, with constant attacks on journalists, political opponents and a retribution campaign against his enemies. He is also on the receiving end of a decade of denunciations depicting him as a Nazi, fascist, dictator, danger to democracy and not a very nice person.

Another major shift is that there are so many more journalistic stars now, from legacy media to online influencers, to the point that some lawmakers have quit (or been retired) to become network and cable contributors, even anchors.

That’s why this essay in the Atlantic, by Michael Scherer, is so revealing.

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Scherer, who previously reported for Time and the Washington Post, says he feels “complicit” in the new world of endless attacks. He wrote this after attending the White House Correspondents’ Association Dinner that erupted in gunfire in the third assassination attempt against President Trump – and unleashed a torrent of comments from idiots who claimed the assault was somehow “staged,” though we watched it unfold on live television. 

He listed a spate of political murders, from Charlie Kirk to the CEO of United Healthcare, and sees the cycle of political violence getting worse.

Scherer once co-authored an article about Trump comparing himself to Napoleon, Alexander the Great and Julius Caesar, with no hint of political violence, that triggered a wave of obscenity-filled attacks against the president. 

Here’s the formula: “The more a story taps an emotional vein—usually outrage or grievance—the more traffic it will tend to attract from social media. I am in the business of writing long and complicated stories full of nuance. Yet I am at the mercy of platforms that want to turn my words into cortisol and endorphins, often for people who will never click the link to read what I wrote. Regardless of my intentions, my work can fuel the false division I despise.”

And aren’t most journalists guilty of this to some degree, whether it’s squeezing a short line onto the platform previously known as Twitter, or slapping a tendentious headline on a podcast? That’s part of the escalation. 

Meanwhile, Kash Patel’s lawsuit may be taking a troubling turn.

MS NOW reported yesterday that there is concern among FBI agents that the bureau has “launched a criminal leak investigation” aimed at the Atlantic journalist who wrote the offending piece, Sarah Fitzpatrick. 

That would be strange, because the story contained no classified information. It was a negative portrayal of his conduct in office and alleged drinking habits. This would, if accurate, mean that Patel was in charge of the alleged probe while pursuing a $250-million suit against the magazine.

A bureau spokesman denied the story, saying: “This is completely false. No such investigation like this exists and the reporter you mention is not being investigated at all.” 

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“If confirmed to be true,” said Editor-in-Chief Jeffrey Goldberg, “this would represent an outrageous attack on the free press and the First Amendment itself. We will defend the Atlantic and its staff vigorously; we will not be intimidated by illegitimate investigations or other acts of politically motivated retaliation.”

Take the denial for what it’s worth. But keep in mind that in January, the FBI, armed with a search warrant, entered the home of Washington Post reporter Hannah Natanson, seized her iPhone and other devices, as part of a leak investigation and still hasn’t returned them – though they include such personal information as her wedding plans. Natanson just won a Pulitzer. 

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First Round Of NHL’s Stanley Cup Playoffs Sees Nearly 70% Ratings Increase

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The average viewership is the largest ever for a Stanley Cup first round in the United States
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