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Hormone therapy boosts weight loss drug results by 35% in women, study finds

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For women struggling with weight gain after menopause, a new study suggests that adding hormone therapy to a popular obesity drug may lead to greater weight loss.

Postmenopausal women lost about 35% more weight when using menopausal hormone therapy alongside tirzepatide — a GLP-1-based, Food and Drug Administration-approved drug for overweight and obesity — compared to those taking the drug alone, according to a Mayo Clinic study.

The findings, published in February in The Lancet Obstetrics, Gynaecology, & Women’s Health, highlight a possible new strategy for addressing weight gain after menopause, when hormonal shifts can increase the risk of obesity, cardiovascular disease and type 2 diabetes.

STOPPING OZEMPIC? NEW STUDY REVEALS SURPRISING WEIGHT REGAIN RESULTS AFTER GLP-1S

“This study provides important insights for developing more effective and personalized strategies for managing cardiometabolic risk in postmenopausal women,” Dr. Regina Castaneda, the study’s first author, said in a statement. 

Researchers analyzed 120 postmenopausal women with overweight or obesity who took tirzepatide for at least 12 months, including 40 who also used hormone therapy and 80 who did not.

Hormone therapy is commonly used to treat menopause symptoms like hot flashes and night sweats, while tirzepatide helps regulate appetite and blood sugar.

WEIGHT-LOSS MEDICATIONS COULD IMPACT SEXUAL HEALTH IN UNEXPECTED WAYS

Women in the hormone therapy group lost an average of 19.2% of their body weight, compared to 14.0% in the non-hormone group — about 35% greater relative weight loss — with more women reaching significant weight-loss thresholds, according to the study.

Despite the results, researchers emphasized that the study was observational and cannot prove cause and effect.

“Because this was not a randomized trial, we cannot say hormone therapy caused additional weight loss,” said Dr. Maria Daniela Hurtado Andrade, an endocrinologist at Mayo Clinic and senior author of the study.

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Outside experts agree that the findings must be interpreted cautiously.

“As with all observational studies, we need to interpret this study with a grain of salt,” Dr. Gillian Goddard, a board-certified endocrinologist, told Fox News Digital. 

Goddard, who is also an adjunct assistant professor of medicine at the NYU Grossman School of Medicine, noted that the findings show a link, but do not prove that hormone therapy, which usually includes estrogen, directly caused the additional weight loss.

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“There may be important differences between the two groups,” she added. “For one thing, the group taking estrogen may be healthier than the groups that didn’t take estrogen … Healthier people are more likely to eat a healthy diet and exercise in addition to taking tirzepatide. That could lead to more weight loss.” 

Symptom relief from the therapy may have also improved sleep and well-being, making it easier for the group to maintain diet and exercise routines, Hurtado Andrade noted.

Researchers also pointed to a possible biological explanation. Preclinical data suggest estrogen may enhance the appetite-suppressing effects of GLP-1-based medications like tirzepatide, according to the study.

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Goddard said that theory is plausible but unproven.

“The other possibility is that estrogen interacts with tirzepatide in some way that makes it more potent,” she said, adding, “We will need randomized studies to get a better handle on that.”

As for safety, experts say using the two together appears safe for most women. However, hormone therapy is not recommended for all patients, especially those with a history of certain cancers, blood clots or other underlying health risks, according to the Mayo Clinic.

Researchers say future randomized trials will aim to confirm the findings and explore whether the combination also improves broader cardiometabolic health outcomes, according to the study.

“If confirmed, this work could speed the development and adoption of new, evidence-based strategies to reduce this risk for millions of postmenopausal women navigating this life stage,” said Hurtado Andrade.

Fox News Digital has reached out to the study authors for comment.

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DHS Arrests Illegal Of Astonishing Crime – Leftist Sympathizers Erupt

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DHS Arrests Illegal Of Astonishing Crime – Leftist Sympathizers Erupt

A newly revealed immigration case is drawing national attention after federal authorities arrested a Mauritanian national accused of using a fraudulent asylum claim to enter the United States before later securing employment as a correctional officer at an Indiana county jail.

According to the Department of Homeland Security, Selah Dine Habib was taken into custody by Immigration and Customs Enforcement after investigators determined that his pending asylum application may have been based on false information. Federal officials allege that Habib entered the United States illegally near Lukeville, Arizona, in March 2023 and was subsequently released into the country under policies implemented during the Biden administration.

DHS officials say Habib sought asylum by claiming he was being persecuted because of his homosexuality. However, authorities later discovered that he married a woman after arriving in the United States, prompting questions about the legitimacy of the original asylum application. Federal officials now believe the claim may have been fraudulent and are pursuing removal proceedings.

The case became even more controversial after local reports revealed that Habib was hired as a correctional officer at the Jay County Jail in Indiana. According to local officials, he was employed after presenting work authorization documents and successfully passing the federal E-Verify employment verification system.

Additional reports indicated that Habib married the daughter of Jay County Sheriff Larry Ray Newton, making him the sheriff’s step-son-in-law. The relationship has intensified scrutiny of the hiring process and raised questions about how an individual with a pending asylum claim and unresolved immigration status was able to obtain a position within a law enforcement agency.

Sheriff Newton reportedly defended the hiring decision, noting that Habib provided documentation authorizing him to work in the United States and passed all required verification checks at the time of employment. Nonetheless, critics argue the situation exposes broader weaknesses in federal immigration screening and employment verification procedures.

The Department of Homeland Security issued a strongly worded statement following the arrest, emphasizing that the Trump administration has taken a more aggressive approach toward immigration enforcement. Officials stated that individuals who enter the country illegally and obtain public-sector positions undermine public trust in government institutions and law enforcement agencies.

Habib is currently being held in ICE custody at a detention facility in Indiana while his immigration case proceeds through the legal system. Reports indicate he is contesting a final deportation order and seeking to remain in the United States despite the allegations surrounding his asylum application.

The arrest comes as immigration enforcement remains one of the most hotly debated issues in American politics. Supporters of stricter border security argue that cases like Habib’s demonstrate how vulnerabilities in the asylum system can be exploited by individuals seeking entry into the country. They also point to the fact that Habib was ultimately able to obtain employment within a county jail as evidence that additional safeguards may be needed.

Meanwhile, immigration advocates caution that each case should be evaluated individually and stress that allegations alone do not constitute proof of wrongdoing until fully adjudicated through the legal process.

As the case moves forward, federal authorities are expected to continue investigating the circumstances surrounding Habib’s asylum application, employment history, and immigration status. The outcome could have broader implications for ongoing debates over asylum reform, employment verification systems, and immigration enforcement policies nationwide.

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Fired CBS Star Roasted After Making Wild On-Air Personal Claim

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Fired CBS Star Roasted After Making Wild On-Air Personal Claim

Former CBS News star Scott Pelley is facing a wave of criticism after comments he made following his departure from the network sparked a fierce debate online about the role of journalists in war zones.

The longtime “60 Minutes” correspondent found himself at the center of controversy after discussing his career and recent firing from CBS News. During an interview reflecting on his decades covering international conflicts, Pelley stated that he had been “in combat” in both Afghanistan and Iraq while reporting from the front lines. The remark quickly spread across social media, where critics accused the veteran journalist of exaggerating his experiences and blurring the distinction between reporting on military operations and actually serving as a combat soldier.

The backlash was immediate. Commentators from across the political spectrum questioned whether a journalist embedded with military units should characterize his experiences as being “in combat.” Many argued that reporters face significant dangers in war zones but are not performing the same role as service members engaged in military operations. Some critics even compared the controversy to past media scandals involving journalists accused of embellishing wartime experiences.

Others defended Pelley, pointing to his long history of reporting from some of the most dangerous regions in the world. Throughout his career, Pelley covered conflicts in Iraq, Afghanistan, Sudan, Syria, and Ukraine. He frequently traveled with U.S. military units and reported from areas where active fighting was taking place. Supporters argue that journalists working in combat zones often face many of the same dangers as the troops they accompany, including enemy attacks, roadside bombs, and hostile fire.

The controversy emerged just days after Pelley’s dramatic exit from CBS News. The veteran correspondent was fired following a highly publicized clash with new network leadership, including editor-in-chief Bari Weiss and recently appointed “60 Minutes” executive producer Nick Bilton. Reports indicate that tensions boiled over during a staff meeting in which Pelley sharply criticized the direction of the iconic news program and accused network leadership of damaging its legacy.

According to multiple reports, CBS executives cited Pelley’s behavior and unwillingness to work with the network’s new leadership team as reasons for his dismissal. Pelley, however, has maintained that his concerns centered on protecting the journalistic standards that made “60 Minutes” one of the most respected news programs in television history.

The dispute over Pelley’s combat comments has added another layer to an already contentious public battle surrounding his departure. While critics continue to mock the wording of his remarks, supporters argue that the focus should remain on his decades of reporting from dangerous locations around the globe rather than on a single phrase used during an emotional interview.

Regardless of where the debate lands, the episode has once again thrust Pelley into the national spotlight at a time when CBS News is undergoing one of the most significant shakeups in its history. As the network continues to reshape its newsroom and “60 Minutes” moves forward without one of its most recognizable faces, Pelley’s comments—and the reaction they generated—are likely to remain part of the broader conversation surrounding journalism, war reporting, and the changing media landscape.

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AOC Just Made A Move That Has Democrats Quietly Panicking

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AOC Just Made A Move That Has Democrats Quietly Panicking

Rep. Alexandria Ocasio-Cortez is facing renewed scrutiny as her political alliance with New York City Mayor Zohran Mamdani continues to draw national attention and fuel debate about the future direction of the Democratic Party.

The progressive congresswoman, one of the most recognizable figures on the American left, has become one of Mamdani’s most prominent supporters. The partnership has energized progressive activists while raising concerns among moderates who worry that the Democratic Party is moving further away from the political center. Ocasio-Cortez has repeatedly praised Mamdani’s leadership and vision for New York City, viewing his rise as part of a broader movement aimed at reshaping Democratic politics.

Mamdani, a Democratic Socialist whose political platform includes expansive government programs and increased taxes on wealthy individuals and corporations, has become a leading figure in progressive politics. Since taking office as mayor, he has pushed proposals ranging from expanded childcare programs to tax increases designed to address New York City’s budget challenges.

For many progressives, the partnership between Ocasio-Cortez and Mamdani represents a blueprint for the future. Supporters argue that both leaders have successfully connected with younger voters and working-class constituencies who feel ignored by traditional political institutions. Their campaigns have emphasized affordability, housing costs, public transportation, and economic inequality as central issues facing Americans today.

Critics, however, argue that the alliance reflects an increasingly socialist direction within the Democratic Party. Some opponents have pointed to endorsements Ocasio-Cortez recently made in New York state legislative races, where she backed several Democratic Socialist candidates advocating policies such as fare-free public transportation, expanded government services, and decriminalization measures that have generated controversy among voters.

The debate comes at a critical moment for Democrats as party leaders attempt to balance competing ideological factions ahead of the 2026 midterm elections. House Minority Leader Hakeem Jeffries and other establishment figures have worked to maintain unity between moderate and progressive wings, but tensions remain visible in key races across the country.

Political observers note that Ocasio-Cortez’s influence within Democratic politics has grown significantly since her upset congressional victory in 2018. Once viewed as a political outsider, she is now considered one of the party’s most influential progressive voices, with endorsements that carry substantial weight among liberal activists and voters. Her support has become highly sought after in Democratic primaries, particularly among candidates seeking to energize grassroots progressive organizations.

Whether the Ocasio-Cortez-Mamdani partnership ultimately strengthens or weakens Democratic electoral prospects remains an open question. Supporters see a movement capable of inspiring a new generation of voters, while critics warn that policies associated with democratic socialism could alienate independents and moderate Democrats in competitive districts.

What is clear is that both figures have become central players in a larger struggle over the Democratic Party’s identity. As elections approach and policy battles intensify, their alliance is likely to remain a focal point in the national political conversation, with supporters and opponents alike closely watching its impact on the future of American politics.

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